Amazon Prime Video announced that the Week 16 showdown between the Los Angeles Rams and Seattle Seahawks will be the first “Thursday Night Football” game featuring two 11-win teams. The Rams and Seahawks are both 11-3, though the Rams have already clinched a postseason spot. Los Angeles holds first place because of a 21-19 victory on Nov. 16.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 16 on a 52-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

There’s no bigger game on the NFL slate this week than the one kicking things off on Thursday. The Los Angeles Rams are visiting the Seattle Seahawks in an NFC West showdown at Lumen Field, with the winner taking over sole possession of first place in the division.

The Seahawks can clinch a spot in the 2026 NFL Playoffs with a win over the Rams on Week 16 Thursday Night Football

Daily Fantasy multimillionaire Mike McClure reveals his daily Fantasy football picks for Seattle vs. Los Angeles on 'TNF'

The Rams (+350) and Seahawks (+700) remain the top two teams in BetMGM’s Super Bowl odds with Week 15 victories — setting up a major NFC West showdown on Thursday night.

As if this game needed a further testimonial as to its gravitas, the Rams (+310) and the Seahawks (+650) are currently the two favorites to win the Super Bowl (the Broncos sit third at +850). Each is 8-1 in their last nine games.

Find out how to watch Los Angeles Rams vs. Seattle Seahawks live streaming online, plus TV channel and game info for this week 16 NFL matchup.