There is currently no cure for Alzheimer’s disease, a type of dementia that an estimated 7.2 million Americans age 65 and ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease ...

An experimental drug developed at Northwestern University has demonstrated further promise as an early intervention for Alzheimer's disease.

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

The humble lab mouse is an essential research tool, helping researchers understand the biological processes that underpin disease development and progression. The ability to observe disease pathology ...

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide. In most cases, this condition occurs as a result of an ...

Researchers based in Paris, France, have explored the potential use of zebrafish larvae as animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These larvae are small and ...

Established in 2002, the Animal and Preclinical Models Core serves to provide specialized capabilities for developing and characterizing numerous CF animal models relevant to CF pathogenesis and ...

Our knowledge of Alzheimer's disease has grown rapidly in the past few decades but it has proven difficult to translate fundamental discoveries about the disease into new treatments. Now researchers ...