Prior COVID-19 vaccination did not stop the immune system from mounting a protective response to the delta and omicron strains, though new mutation-specific antibody production dipped slightly, ...
Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes M6P ...
Diversity is good, especially when it comes to antibodies. It's long been known that a gene assembly process called V(D)J recombination allows our immune system to mix and match bits of genetic code, ...
It's long been known that our immune cells mix and match bits of genetic code to make new kinds of antibodies to fight newly encountered threats. But how these different gene segments come together ...
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control ...
Antibody-drug conjugates (ADCs) have been in development for decades, but only about a dozen have received FDA approval. Clearly, ADCs still have some major challenges. Yet they have done little to ...