Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...
For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...
Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...
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Natural molecular brake prevents uncontrolled DNA replication in cells
For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...
DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...
If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...
This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...
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