Having a bye week makes it seem like an even longer time, but the Buffalo Bills are back in the win column in Week 8. The Bills (5-2) took and and beat the Carolina Panthers in a rout on Sunday. It was a 40-9 final.

James Cook rushed for 216 yards and two touchdowns and the Bills defense had seven sacks in a 40-3 win over the Panthers.

The Buffalo Bills' defense was dominant on Sunday, generating seven sacks and three turnovers in a 40-9 victory.

The Falcons are back on national TV in Week 6, hosting the Buffalo Bills on ESPN's Monday Night Football. Chris Fowler, Dan Orlovsky an Louis Riddick will be in the broadcast booth for tonight's game. Atlanta still has three other prime-time games, including a Week 7 matchup against the San Francisco 49ers.

In a massive AFC East clash on "Sunday Night Football" in Week 5, the New England Patriots defeated the Buffalo Bills. Here's how it happened:

ORCHARD PARK - After just five weeks, there are no more undefeated teams in the NFL. Following the Philadelphia Eagles loss to the Denver Broncos Sunday afternoon, the Buffalo Bills were the last remaining team without a defeat heading into their Sunday ...

Josh Allen hit Khalil Shakir for 54-yard TD, extending the Buffalo Bills' lead over the Carolina Panthers.

Buffalo Bills defensive end Greg Rousseau strips the ball from Carolina Panthers quarterback Andy Dalton and Bills cornerback Christian Benford recovers the ball during Week 8 of the 2025 NFL season.