Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...
The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...
The TP63 gene, an important member of the TP53 family, contains two independent promoters that drive the transcription of TAp63 and ΔNp63, respectively. Through alternative splicing, TAp63 and ΔNp63 ...
How does obesity affect insulin production? Researchers are shining light on new stages of the ERK pathway. Researchers at the Tohoku University Graduate School of Medicine have uncovered a key ...
A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
New review reveals how non-genomic estrogen signaling undermines treatment response and fuels tumor progression Hormone receptor–positive breast ...
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