Using a blend of computer modeling, structural and cell-based studies, scientists at The Wertheim UF Scripps Institute have ...

Objective–Endothelial progenitor cells (EPCs) are decreased in number and function in type 2 diabetes. Mechanisms by which this dysfunction occurs are largely unknown. We tested the hypothesis that a ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Cells experience many different types of stress, such as starvation or stress caused by too much salt or too high a temperature. Insulin signals respond to such stress signals by sending the protein ...

Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within ...

Insulin sensitivity reflects how effectively cells respond to insulin’s signal to absorb glucose, and everyday eating habits ...

Small, everyday food decisions — not extreme diets — play a powerful role in how your body manages blood sugar and energy ...