Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Researchers have created a detailed map of chemical modifications to DNA that occur in the human brain from the earliest stages of fetal development through old age. A new study published in Cell ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there are things beyond the DNA sequence,” says Xiaoqi Feng, a plant geneticist at ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

A Japanese research team has demonstrated that the use of antisense oligonucleotides (ASOs) with modified bases and sugars can enhance the effectiveness of targeting diseases in the central nervous ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

A live C. elegans animal with the mitochondria in its nervous system decorated with red and green fluorescent proteins. “Mitochondrial DNA is essential for cell function,” Dr Hahn said. “But as we age ...