A new 3D connective tissue model gives researchers a sophisticated tool to understand the underlying mechanisms of connective tissue disorders and test potential treatments. To find treatments for ...

The Calve Musculoskeletal Extracellular Matrix Lab characterizes the material properties of assembling tissues to establish design parameters for regenerative therapies. They are particularly ...

University researchers have developed a new connective tissue model to study disorders like fibrosis, a type of scarring that occurs when damage to the body causes normal tissue to be replaced by hard ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

Despite intensive studies, the clinical opportunities for patients with fibrosing liver diseases have not improved. This will be changed by increasing knowledge of new pathogenetic mechanisms, which ...