cyclic AMP and cyclic GMP are universal second messengers and are sensed by receptor proteins that contain cyclic nucleotide binding (CNB) domains. In mammal, CNB domains are found in protein kinase A ...

Scientists have developed a computational method based on large-scale molecular dynamics simulations to predict the cell-membrane permeability of cyclic peptides using a supercomputer. Their protocol ...

This is a preview. Log in through your library . Abstract HD-GYP is a protein domain of unknown biochemical function implicated in bacterial signaling and regulation. In the plant pathogen Xanthomonas ...

Let F be the function field of a smooth curve over the p-adic number field ℚp. We show that for each prime-to-p number n the n-torsion subgroup H2(F, μn) = n Br(F) is generated by ℤ/n-cyclic classes; ...

“We are excited to introduce our cyclic-di-GMP assay to the scientific community,” said the business development manager of Amerigo Scientific. “By providing a simplified and efficient method for ...