The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...
DNA’s iconic double helix does more than “just” store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
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Unusual i-DNA structure shown to regulate genes and cancer
DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...
Model predicts effect of mutations on sequences up to 1 million base pairs in length and is adept at tackling complex ...
Study Shows How Melting Point Analysis Infers the Presence of and Identifies SNPs The melting temperature (T m) of a PCR product is dependent on both the length and sequence of the DNA. Melting curve ...
Base pairs are at the heart of molecular biology information. Recognized ever since their discovery by Watson and Crick in 1953, the base pair provides, among other things, rules for copying DNA, ...
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