Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Nearly 7 million Americans have Alzheimer's disease, and this number is predicted to double by 2060. While aging and genetic predisposition are the most important risk factors for Alzheimer's, ...

Study reveals how aging accelerates molecular changes in the brain, offering new hope for tackling cognitive decline and mental illness. Resource: Single-nucleus transcriptomic profiling of human ...

In single-cell research, understanding how stochasticity in gene transcription influences phenotypic heterogeneity within isogenic cell populations represents a fundamental question. Fluctuations in ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

New study reveals gene expression differences in brain regions tied to addiction, highlighting pathways for innovative alcohol use disorder treatments and drug repurposing opportunities. Study: Gene ...