Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance pathway that degrades aberrant mRNAs containing premature termination codons (PTCs). NMD is triggered upon the assembly of the UPF ...
The EJC exemplifies the dynamic aspect of messenger ribonucleoprotein (mRNP) particles and its importance in eukaryotic gene expression 1. As a consequence of splicing, assembly of the EJC occurs ...