Clinical and economic value of comprehensive genomic profiling in patients with advanced solid cancers using Australian real-world data: Preliminary analyses. This is an ASCO Meeting Abstract from the ...

Mapping diverse mutations within a cancer hotspot revealed that distinct variants drive tumor growth to different extents, which could guide anticancer therapies.

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk ...

ATP-binding cassette (ABC) transporters are transmembrane proteins essential for the biliary secretion of bilirubin, bile acids, phospholipids, and ...