A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

The researchers unravel the exact mechanism of how developmentally active enhancers become repurposed in a tumor context and show the relevance of this repurposing event for cancer. University of ...

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called ...

Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called ...

In part 2 of this webinar, Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, will reveal new data that illustrates how the Hodges Lab is utilizing the 6-base genome to ...

Switches' in our DNA that affect gene activity in cells could be crucial to understanding and possibly treating Alzheimer's ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...