New research has revealed the means by which cells accomplish programmed DNA replication arrest. The work describes the conditions that require a replication fork to stop, and in doing so explain why ...

Replication fork reversal is a complex transaction that requires the coordinated unwinding and annealing of parental and newly synthesized strands at the replication fork. Replication fork reversal is ...

Mechanism of genome replication arrest provides pioneering insight about cell life span and aging A research collaboration between the Medical University of South Carolina, the Institute of Human ...