The human gut is the largest mammalian organ to produce hormones. In response to food, the hormone-producing cells in this organ secrete dozens of peptides. Now, researchers from the Organoid group ...

The gut–islets axis connects nutrient sensing in the intestine with insulin secretion from the pancreas and plays an essential role in glucose regulation. GLP-1 released by intestinal L cells can ...

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion. In ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve ...

In the current study, several immune-related pathways, particularly those involving IL-6, were found to be associated with both melatonin secretion and ADHD. Taken altogether, the study’s findings ...

Medical Oncologists' Attitudes and Practice in Cancer Pain Management: A National Survey Between 1997 and 2008, 192 pediatric patients with localized primary brain tumors (ependymoma, n = 88; ...

Did you ever wonder where that sudden feeling of hunger comes from when your empty stomach rumbles? Thousands of hormone-producing cells, or enteroendocrine cells, scattered throughout your stomach ...

The discovery of a gut-to-brain regulation pathway in flies calls for additional consideration on how certain medications, especially GLP-1 agonists, can be used to treat obesity and diabetes in ...