Primary sclerosing cholangitis (PSC) is a chronic, progressive inflammatory disease characterized by fibrosis and bile duct stricturing, which ultimately leads to cirrhosis and liver failure. PSC is ...

Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, ...

IBD risk gene PTPN2 protects the gut by limiting invasion and growth of harmful E. coli, but when function is reduced, ...

Patients with inflammatory bowel disease (IBD) showed significantly lower muscle strength than matched healthy individuals, with women showing particularly worse nutritional status in terms of ...

Normally, PTPN2 helps maintain gut health by controlling inflammation and supporting a balanced gut microbiome. However, some ...

Inflammatory bowel disease (IBD) patients face significant health care access barriers, leading to medication rationing and adverse health outcomes. Key issues include appointment availability and ...

Allogeneic HSCT achieved 92% sustained, medication-free remission and 100% survival in children with monogenic IBD, highlighting its potential as a transformative treatment. Monogenic IBD, ...

ORLANDO -- Major cardiovascular event risk in patients with inflammatory bowel disease (IBD) was no greater with Janus kinase (JAK) inhibitors than with tumor necrosis factor (TNF) inhibitors, ...

Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, ...