Penn State plays its first home game Saturday since James Franklin was fired. The Nittany Lions will play the Indiana Hoosiers in Week 11 of the college football season in the program’s sixth Big Ten game of the year. Here are some final thoughts and predictions ahead of the matchup.

Penn State’s opponent this week is the number two-ranked Indiana Hoosiers. What’s been going well for Indiana this season that has them undefeated so far? Well, analyst for FOX59/CBS4 Sports Chris Widlic says that its everything.

If this Penn State team played No. 2 Indiana 10 times on a neutral field, the Hoosiers would probably win all 10 games. But Curt Cignetti’s 9-0 Hoosiers have to come to Beaver Stadium for Saturday afternoon’s Big Ten matchup.

Penn State, of course, is unranked in the inaugural CFP rankings after losing its fifth straight game. Still, Indiana coach Curt Cignetti found a ranking to pitch his team in girding against the upset as 13.5-point favorites. Hello, ESPN FPI!

Find single game tickets to the Indiana Hoosiers vs. Penn State Nittany Lions college football Week 11 matchup on Saturday, November 8, 2025 at West

Vaughn Dalzell and Eric Froton favor the Indiana Hoosiers' and their strong rushing offense to take down the Penn State Nittany Lions' struggling defense in their Week 11 matchup.

Curt Cignetti's Hoosiers have a potentially challenging road test Saturday at Penn State. Here's the kickoff time and TV information, plus more game details.

Indiana: Cal transfer Fernando Mendoza (15) has blossomed into a star with the Hoosiers. He’s passed for 25 touchdowns against only four interceptions. Mendoza is also a threat on the ground with four scores. He is averaging 4.4 yards per carry.