DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Antimicrobial resistance (AMR) poses one of the greatest threats to global public health, with excessive antibiotic use driving the emergence of ...

MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

Researchers from the School of Dental Medicine and international collaborators from Dresden Germany investigated the effects of training the innate immune system in experimental models of chronic ...

Researchers highlight how exercise and dietary strategies may complement immunotherapy by improving immune function, tumour perfusion, and quality of life.