Objective–Endothelial progenitor cells (EPCs) are decreased in number and function in type 2 diabetes. Mechanisms by which this dysfunction occurs are largely unknown. We tested the hypothesis that a ...

Using a blend of computer modeling, structural and cell-based studies, scientists at The Wertheim UF Scripps Institute have ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

AMOLF researchers discovered a mysterious interplay of insulin signals in the worm C. elegans. The insulin-driven protein DAF ...

Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within ...

Explore innovative Type 2 diabetes drugs that enhance insulin sensitivity and reduce side effects from older treatments.

Insulin sensitivity reflects how effectively cells respond to insulin’s signal to absorb glucose, and everyday eating habits ...

Small, everyday food decisions — not extreme diets — play a powerful role in how your body manages blood sugar and energy ...