"By cleverly combining new techniques for analyzing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia," predicts Professor John ...

Once disregarded as “junk DNA,” scientists now know that this molecular dark matter is crucial for determining gene activity ...

Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

The authors used a combination of super-resolution imaging techniques and liquid pressure flow to fine-tune the stretch ratio of a DNA molecule, improving the lateral resolution of side-by-side ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...