The lysosome was once thought of as the trash can of the cell, a dead-end destination where cellular debris was sent for disposal. But a growing body of research shows that this enzyme-filled vesicle ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, ...

At a conference in Maine during the summer of 2008, the biochemist David Sabatini stood before an audience of his peers, prepared to dazzle them with a preview of unpublished results emerging from his ...