Week 12 in the NFL featured several big breakouts and setbacks. Who were the biggest winners ahead of the Thanksgiving slate?

Injuries continued to pile up during Week 12 of the 2025 NFL season, headlined by Buccaneers QB Baker Mayfield.

In Week 12 of the 2025 NFL season, how many underdogs emerged victorious? Below, we provide a comprehensive list of the teams that pulled off an upset last week. FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Don't miss tonight's Broncos vs Commanders game on NBC and Peacock. Live coverage begins with Football Night In America at 7 PM ET.

The NFL has seen 12 weeks of the season come and go. In the process, teams have emerged as contenders, others have sunk, and through it all, team needs have started to unfold as their front offices get ready for the NFL Draft that will be here before we know it.

Week 13 of the 2025 season wraps up with the 10-2 New England Patriots hosting the 2-10 New York Giants in primetime on Monday night. This matchup could feature

Branch has been fined in back-to-back games and now five times this year. There were three Lions fined altogether from the Week 12 game against the Giants.

The Steelers' Aaron Rodgers is off the injury report for Sunday's game against the Bills after finishing the week with consecutive full practices following a Week 12 absence due to a wrist injury. Rodgers' return improves the outlook for Pittsburgh's skill-position weapons, and it also bumps Mason Rudolph back down to his customary No. 2 role.