New mechanism determined for passive transport of biomolecules through the nuclear pore complex of cells. Research can help guide the development of future therapeutics for human diseases such as ...

A structural study has revealed important clues about how a cell protein factory is itself constructed. Ribosomes are macromolecular factories that produce proteins according to instructions given by ...

The human NPC is composed of approximately 34 nucleoporin proteins. The interior, or “symmetric,” core is composed of an inner ring, and two outer rings that sit on either side of the nuclear envelope ...

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications ...

Nuclear pore complexes are more dynamic than previously thought, reshaping our understanding of a vital transport process in cells. An international study led by the University of Basel (Switzerland) ...

Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...

Students learn about the nucleus in ninth grade biology — it's the inner sanctum of biological cells, where the genome resides with the blueprints for cells to make proteins that are the ...

An international study led by the University of Basel has discovered that nuclear pore complexes—tiny gateways in the nuclear membrane—are not rigid or gel-like as once thought. Their interiors are ...

A model of transport through the nuclear pore complex. The blue spheres represent macromolecules that do not interact with the selectively permeable barrier of the complex, while the red spheres ...

Proteins are most well-known for their intricate structures. The α-helices and β-sheets that form from interactions between sidechains create distinct shapes that, along with the specific amino acid ...

A new study has revealed how HIV squirms its way into the nucleus as it invades a cell. Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it -- inventing all ...