The TULA family proteins, comprising predominantly TULA-1 (also known as UBASH3A/STS-2) and TULA-2 (UBASH3B/STS-1), are increasingly recognised as pivotal modulators of T cell receptor (TCR) ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

In atopic dermatitis, psoriasis and other dermatologic diseases, T cells lose tolerance to self-antigens, triggering the autoimmune response that leads to abnormal skin cell proliferation and ...