Researchers have investigated the importance of the Notch pathway for the evolution of tooth morphology. Mutations in this signalling pathway can lead to defective structures in tooth enamel. Studies ...

Cilk1 deficiency disrupts normal tooth development by altering primary cilia function and weakening Hedgehog signaling. This reduction triggers extra diastemal teeth, enlarges them under further ...

The evolution and development of complex molars as a key innovation in mammals have long been of interest yet remain poorly understood. With reference to century-old theories and modern findings, we ...

The study of dental education and student learning in anatomy has evolved into a multidisciplinary field that bridges traditional didactic instruction with innovative technological approaches.

Researchers demonstrated that declining Hedgehog signaling from Cilk1 loss produces stepwise changes in tooth formation and morphology CHENGDU, CHENGDU, CHINA ...