For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Phenotypic 3D cell models incorporate tissue architectures and extracellular matrices to recapitulate the complexity of the ...

A robust model, such as aProximate TM, is required to study renal dysfunction and perform in vitro kidney disease modeling. This model expresses all transporters specialized in drug, solute, and ...

Biological assailants like fungi, bacteria, and viruses continuously test natural defenses that have evolved over millennia. Newer and stranger particles that originate from burning fuels, harmful ...

Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-on-Chip" ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Advances in biofabrication and 3D in vitro model systems are transforming biomedical research, drug development, and toxicity testing. However, despite ...

In this Innovation Spotlight, Treutlein shares her excitement of using organoids to model the human brain, harnessing AI to accelerate laboratory discoveries, and discusses how massive-scale ...

Understanding how the digestion process influences and alters the composition and structure of food is essential for food ...

In a breakthrough for the advanced study of gut health, scientists have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin.