NeuroDex and Stanford Publish First Blood-Based Evidence of CNS Target Engagement for GLP-1 and PPARγ Agonists

NATICK, MA, UNITED STATES, April 22, 2026 /EINPresswire.com/ -- NeuroDex and Stanford Researchers Publish First ...
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Phytic acid-based nanomedicine against mTOR for metabolic dysfunction-associated steatohepatitis therapy

CePA exerts a liver-targeted mTOR repressive function, alleviating MASH progression and fat accumulation in high-fat diet-fed mice. Metabolic dysfunction-associated steatohepatitis (MASH) is one of ...
GEN

Neuroblastoma Tumor Growth in Mice Suppressed by Blocking Enzyme to Inhibit mTOR Signaling

Neuroblastoma is the most common tumor among children under a year of age, and while in its gentlest form neuroblastoma can regress on its own, it can also take an aggressive form, with high-risk ...
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Investigation of ferroptosis and mTOR signaling in chromophobe renal cell carcinoma (ChRCC).

Circulating kidney injury molecule-1 (KIM-1) in association with kidney injury biomarkers and outcomes in metastatic renal cell carcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...
GEN

Lifespan in Mice Shortens with Increase in Nutrient Signaling to mTOR

As the aging population increases, the race to unpack the molecular understanding of aging heats up. The rapamycin (mTOR) complex 1 (mTORC1) is known to be a key component of multiple functions of the ...
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Schematic model illustrating the NO-mTOR signaling axis in neuroblastoma. (IMAGE)

Schematic model illustrating the NO-mTOR signaling axis in neuroblastoma. Under basal/pathological conditions (left panel), and nNOS inhibition (right panel). Credit must be given to the creator.