Fernando Tatis Jr. and Manny Machada hit leadoff homers and the San Diego Padres beat the Arizona Diamondbacks 4-3 on Thursday night to split a four-game series.

The Philadelphia Phillies (54-39) and the San Diego Padres (50-43) open a 3-game series Friday at Petco Park in San Diego. First pitch is scheduled for 9:40 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Phillies vs. Padres odds and make our expert MLB picks and predictions for the best bets.

The Arizona Diamondbacks hit four home runs, including a Geraldo Perdomo grand slam, in their win over the San Diego Padres on July 9.

Diamondbacks starter Brandon Pfaadt entered the game with a 5.42 ERA and went eight innings for the first time in his career. The Padres scored both their runs and managed four hits against the right-hander, who had not had a quality start in any of his eight starts leading up to Wednesday.

Luis Arraez homered in the seventh inning to break up a scoreless tie Tuesday night and five San Diego Padres pitchers combined on a three-hit shutout in a 1-0 win over the visiting Arizona Diamondbacks.

Arizona Diamondbacks starting pitcher Brandon Pfaadt puts together a dominant start against the San Diego Padres in San Diego, on July 9, 2025.