Objectives Sleep-disordered breathing is a key childhood complication in children with achondroplasia. This retrospective study aimed to document the prevalence of sleep-disordered breathing in ...

This series of systematic reviews was commissioned by WHO in July 2022 to inform their guideline review process. The aim was to identify the current evidence for developing WHO guidelines for the ...

A review of the history of confidential enquiries The Confidential Enquiry into Maternal and Child Health (CEMACH) was established in April 2003. It replaces CESDI (the Confidential Enquiry into ...

Conclusion Consumption of slush ice drinks containing glycerol may cause a clinical syndrome of glycerol intoxication in young children, characterised by decreased consciousness, hypoglycaemia, lactic ...

Tablets are safer, more convenient and cheaper than liquid medications. Children and young people (CYP) often remain on liquids due to habit, reluctance to change or staff and parents’ lack of ...

Premature adrenarche (PA) is characterised by early maturation of the zona reticularis of the adrenal gland before 8 and 9 years in girls and boys, respectively.1 Biochemical analysis of androgens is ...

> Optimism is a good characteristic, but if carried to an excess, it becomes foolishness. Theodore Roosevelt1 We would define an innovative therapy as any newly introduced treatment, or a new ...

Objective The aim of this research was to ascertain the effectiveness of current electronic prescribing (EP) systems to prevent a standardised set of paediatric prescribing errors likely to cause harm ...

Chronic pain is an important clinical problem affecting significant numbers of children and their families. The severity and impact of chronic pain on everyday function is shaped by the complex ...

Objective Neural tube defects (NTDs) are a preventable folate deficiency disorder; increasing folic acid intake through food fortification increases serum and red blood cell folate and reduces the ...

Background Cognitive ability and socioemotional behaviour during childhood have independently been shown to impact educational outcomes. The extent to which their co-development predicts these ...

Objective Horner’s syndrome (HS) is characterised by a triad of ocular miosis, ptosis and anhidrosis. HS may be a subtle sign of occult pathology in otherwise asymptomatic children, neuroblastoma (NBL ...