The data shows that downregulating PU.1 promotes the expression of immunoregulatory proteins on microglia that help protect cognitive function.

Harvard University scientists have developed the first menstruating mice. This breakthrough allows for new research into ...

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate ...

Lacking a common protein may affect how muscles respond to testosterone, potentially affecting athletic performance and age-related muscle loss, according to a new study led by an Australian research ...

In Alzheimer's disease—the leading cause of dementia—microglia, the brain's immune defenders, can act as both protectors and ...

The human genome is riddled with relics of viral infections—bits of DNA from viruses that have been inserted in human DNA ...

Felzartamab, an investigational anti-CD38 monoclonal antibody, is a potentially differentiated therapeutic candidate with promise for a broad range of immune-mediated diseases ...

Microglia (green) responding to aggregated beta-amyloid plaques (blue) in the mouse cortex. (Credit: Jessica M. Crowley) A ...

Tatsuya Nobori brings high-resolution multiomic approaches to plant biology to map how plants interact with microbes on a ...

In Alzheimer's disease, the leading cause of dementia, microglia-the brain's immune defenders-can act as both protectors and aggressors, shaping how the disease progresses.

A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player in prostate ...

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes ...