Cyclone is a portable gene-switch system that uses acyclovir to reversibly control gene expression with minimal toxicity.

Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an ...

Approach that uses cell’s own strategy of liquid-liquid phase separation protects synthetic modifications from being washed away by the tide of cell growth.

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" ...