The Jaguars are set to enter hostile territory in Week 16 when Lawrence and company travel to face the Denver Broncos and a hostile Mile High Stadium crowd. On Wednesday, Lawrence discussed the challenge the Jaguars' offense will face in terms of their operation.

The Denver Broncos are looking healthy as most guys listed are full participants on Wednesday. Ben Powers also returned.

The Jacksonville Jaguars are headed to Denver in Week 16 of the 2025 NFL season, facing the Broncos in another AFC matchup. The game will kick off at 1:00 p.m. ET from Empower Field at Mile High. Catch up on all the action, behind-the-scenes moments, and full game coverage. ⬇️

At this point, there's no more denying that the Jacksonville Jaguars are one of the best teams in the 2025 NFL season.

How to watch, listen to and live stream the Broncos’ Week 16 home matchup against the Jacksonville Jaguars on Sunday, Dec. 21, 2025.

The Jaguars will enter a hostile environment in Week 16 against the Broncos. They thrive off of adversity, though and have learned plenty this year.

The Broncos wore white helmets at practice on Wednesday, a sign that they'll wear white caps with orange jerseys against the Jaguars.

Trevor Lawrence was sharp throughout, passing for 330 yards with five touchdowns and no interceptions. His early scramble for a touchdown and a perfectly dropped 33-yard throw on third-and-long late in the second quarter highlighted his command of the offense.

Marcedes Lewis is on the Broncos' practice squad but ahead of Denver's game against the Jacksonville Jaguars, he caught up with The Times-Union.