A win in Week 18 would mean the 49ers sweep the Seahawks and win the head-to-head tiebreaker (assuming their records match).

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle ...

Brandon Aiyuk hasn't been a part of the San Francisco 49ers' season, and Kyle Shanahan opened up with his regret amid the ...

It's another week of multiple players on the San Francisco 49ers missing from practice. At this point in the season, it's a ...

INDIANAPOLIS — The Indianapolis Colts and San Francisco 49ers understand the stakes on Monday night. Both find themselves in ...

Making the playoffs before this season wasn’t a crazy idea to suggest about the San Francisco 49ers. What was a crazy idea is ...

See who's in and who's out for the Week 16 matchup between the San Francisco 49ers and Indianapolis Colts on December 22, ...

Brandon Aiyuk has not played this season after suffering a torn ACL and MCL in Week 7 of the 2024 campaign, and San Francisco ...

The Indianapolis Colts are just trying to get into the playoffs. The San Francisco 49ers are playing for a division title and ...

Brandon Aiyuk’s future, or rather the lack thereof, with the 49ers was settled this past Saturday when the team placed him on ...

Shane Steichen said DeForest Buckner is ready for more work, Bernhard Raimann, Sauce Gardner out but progressing ...

The San Francisco 49ers have a big Week 16 Monday Night Football clash against the Colts, and here are bold predictions.