BACKGROUND Antenatal screening for cystic fibrosis has been endorsed by the US National Institutes of Health. Edinburgh is the only city in the UK with an established routine antenatal screening ...

The most recent in a series of dangerous social media trends has seen children ingesting large quantities of nutmeg in an attempt to gain a natural ‘high’. Over the past 20 years, there has been a ...

The incidence of respiratory depression following treatment of prolonged seizures with benzodiazepines is variable in the literature. We retrospectively reviewed the charts of children treated for ...

Tablets are safer, more convenient and cheaper than liquid medications. Children and young people (CYP) often remain on liquids due to habit, reluctance to change or staff and parents’ lack of ...

> Optimism is a good characteristic, but if carried to an excess, it becomes foolishness. Theodore Roosevelt1 We would define an innovative therapy as any newly introduced treatment, or a new ...

Objective The aim of this research was to ascertain the effectiveness of current electronic prescribing (EP) systems to prevent a standardised set of paediatric prescribing errors likely to cause harm ...

Conclusion Consumption of slush ice drinks containing glycerol may cause a clinical syndrome of glycerol intoxication in young children, characterised by decreased consciousness, hypoglycaemia, lactic ...

Objective Neural tube defects (NTDs) are a preventable folate deficiency disorder; increasing folic acid intake through food fortification increases serum and red blood cell folate and reduces the ...

This series of systematic reviews was commissioned by WHO in July 2022 to inform their guideline review process. The aim was to identify the current evidence for developing WHO guidelines for the ...

Premature adrenarche (PA) is characterised by early maturation of the zona reticularis of the adrenal gland before 8 and 9 years in girls and boys, respectively.1 Biochemical analysis of androgens is ...

Objectives To estimate the incidence of clinically diagnosed congenital adrenal hyperplasia (CAH), clinical features and age at first presentation. To assess the potential benefit of newborn screening ...

Objective Routine varicella zoster vaccination for children aged 18 months began in Australia from November 2005. The aim of this study was to compare the current incidence and outcomes of congenital ...