Before each NFL season, NFL media releases its list of top 100 players as voted on by NFL players.

While it's unclear if San Francisco 49ers wide receiver Brandon Aiyuk will play another snap for the team, quarterback Brock ...

His lack of productivity since his return has been head-scratching, but offensive coordinator Klay Kubiak on Thursday in a ...

The San Francisco 49ers have a bit of a scare to deal with as their star running back was limited in the team's second Week ...

Former Seahawks cornerback Richard Sherman had one of the most-viral moments in NFL history against the 49ers. Now, we know ...

Philip Rivers surprised everyone and returned to the NFL this week after 5 years. Would Patrick Willis be willing to do the ...

The San Francisco 49ers are getting some help in their front seven, as defensive end Yetur Gross-Matos is practicing on ...

Eli Lilly is investing $6B in a Huntsville, Ala., plant to make weight-loss and other medicines. Here’s what we know about ...

The San Francisco 49ers didn't get the best possible news from their first Week 15 practice report, but it wasn't all bad.

The San Francisco 49ers added a veteran, former All-Pro linebacker and he's already dealing with an injury problem.

While the Rivers return has been viewed with a ton of skepticism, 49ers head coach Kyle Shanahan isn't convinced it's a crazy ...

There's so much going on around Knoxville throughout the holiday season — tree lightings, parades, festivals and more — that ...