The Indianapolis Colts are currently riding a four-game losing streak. It makes their matchup perfect timing for the San ...

Colts All-Pro cornerback Sauce Gardner will miss his third full game Monday night against the San Francisco 49ers with a calf ...

The Indianapolis Colts' defense will get a big boost against the San Francisco 49ers on Monday Night. Head coach Shane ...

The Colts will host the 49ers at Lucas Oil Stadium for their lone primetime matchup of the season. 44-year-old Philip Rivers will get his second start of the year as the Colts try to put an end to a ...

The 49ers defense is zeroing in on stopping the run as the playoff push begins, starting with RB Jonathan Taylor and the Colts.

GM John Lynch defends WR Ricky Pearsall, pushing back on the injury-prone label as San Francisco prepares for a pivotal game vs. Colts.

Win,’ head coach Jim Harbaugh says of Sunday’s matchup. ‘I know the scenarios are win and something else happens, you know? So, the big part of that is win.’ ...

The Indianapolis Colts will see the return of a key player against the San Francisco 49ers on Monday Night Football in Week ...