Set your Week 16 fantasy football lineups for the playoffs in Round 2. Click to read start 'em, sit 'em advice, injury inactive news, and pregame reports that provide insider fantasy tips.

Yet, nothing changes this week as McCarthy has another favorable spot against a bad Giants defense that ranks just 28th in EPA/Play Allowed and 21st in Dropback EPA Allowed. The Lions have the highest ...

Week 16 got underway with a huge NFC West showdown between the Seattle Seahawks and Los Angeles Rams. The matchup didn't just determine who holds first place in the division, but it also gave the ...

Our latest 2026 NFL mock draft has a few pieces falling into place, though there are still several major unknowns - including ...

Our Buccaneers vs. Panthers SGP for Week 16 likes Baker Mayfield, Sean Tucker, and Tampa's offense to do damage.

This is the week when the standings start breathing down everyone’s neck. Week 16 brings a full menu of playoff pressure, ...

Must-win game for Lions? Can Dallas still make the postseason? Picks, predictions and stats for every Week 16 game.

Cleveland's defensive superstar needs just 1.5 sacks to break the single-season record, but Buffalo has the perfect quarterback and gameplan to stop Garrett's pursuit of NFL immortality.

NFL Week 16 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs ...

Now 10-4 overall on the season after an exhilarating 16-13 victory over the Chiefs, the Chargers look to continue their march ...

Kevin Harlan and Trent Green will be on the call again for CBS. Here is the broadcast map from 506Sports.com, and the Chiefs’ ...

The NFL’s balance of power took another sharp turn in Week 15, and Tom Brady’s latest rankings capture a league in flux.