Thorax

Time to diagnosis and long-term outcomes for adults presenting with breathlessness

Background The impact of delays to diagnosis for individuals presenting with chronic breathlessness is unknown. We ...
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Effects of inhaled salbutamol in exercising non-asthmatic athletes

BACKGROUND Beta-2 agonists such as salbutamol are used, not only by asthmatic athletes to prevent exercise induced asthma, but also by non-asthmatic athletes as a potentially ergogenic agent. We have ...
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Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores

Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...
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Long-term multicentre randomised controlled study of high frequency chest wall oscillation versus positive expiratory pressure mask in cystic fibrosis

1 Division of Paediatric Respirology and Department of Physiotherapy, Cystic Fibrosis Clinic, BC Children's Hospital and University of British Columbia, Vancouver, British Columbia, Canada 2 Division ...
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Side effects of aminoglycosides on the kidney, ear and balance in cystic fibrosis

1 Child Health and Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham, UK 2 Children's Renal and Urology Unit, Nottingham University ...
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Lung function and mortality in the United States: data from the First National Health and Nutrition Examination Survey follow up study

1 Air Pollution and Respiratory Health Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, ...
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Written action plans for asthma: an evidence-based review of the key components

Hunter Medical Research Institute, Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, NSW, Australia Correspondence to: Dr P G Gibson Hunter Medical Research Institute, ...
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Biochemical markers of cardiac dysfunction predict mortality in acute exacerbations of COPD

1 Respiratory Research Unit, Department of Respiratory Medicine, Waikato Hospital, New Zealand 2 Department of Anaesthesia, Waikato Hospital, New Zealand 3 Department of General Medicine, Waikato ...
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Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment

1 Department of Pathology, University of British Columbia, Vancouver, BC, Canada 2 Department of Medicine, University of British Columbia and Head, Respiratory Division, St Paul’s Hospital, Vancouver, ...
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Microbial aetiology of community-acquired pneumonia and its relation to severity

4 Department of Infectious Diseases, Hospital Clínic, Barcelona, IDIBAPS, Spain 5 Centro de Investigación Biomédica En Red-Enfermedades Respiratorias (CibeRes, CB06/06/0028), Instituto de Salud Carlos ...
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β-Actin and GAPDH housekeeping gene expression in asthmatic airways is variable and not suitable for normalising mRNA levels

1 Department of Respiratory Medicine, Alfred Hospital and Monash University Medical School, Melbourne 3181, Australia 2 Department of Epidemiology and Preventive Medicine, Alfred Hospital and Monash ...
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The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and healthcare providers

There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind ...