It's another week of multiple players on the San Francisco 49ers missing from practice. At this point in the season, it's a ...

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle ...

INDIANAPOLIS — The Indianapolis Colts and San Francisco 49ers understand the stakes on Monday night. Both find themselves in ...

The San Francisco 49ers are preparing for their Week 16 contest against the Indianapolis Colts on Monday night at Lucas Oil ...

JJ Stankevitz from the Indianapolis Colts previews Week 16 "Monday Night Football", with one-on-one interviews featuring San ...

Tennessee Titans defensive tackle Jeffery Simmons is grateful his mother wasn’t at his house watching him on TV when burglars ...

NFL Week 16 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs ...

The San Francisco 49ers could have a full complement of wide receivers when they visit the Indianapolis Colts in Week 16.

San Francisco would have a better chance at the No. 1 seed in the NFC playoffs if Seattle can pull off the victory at home.

Colts’ Jonathan Taylor; Ricky Pearsall Jr. doesn’t practice but Kyle Shanahan likes his chances to play Monday.

NFL Insider Tom Pelissero breaks down the playoff clinching scenarios around the NFL in Week 16. San Francisco 49ers have a shot to clinch on "Monday Night Football" with a win. Watch the NFL's ...

Brock Purdy had no excuses against the Tennessee Titans and had to have a big game against their weak pass defense. Fortunately for the San Francisco 49ers, the ...